After a few welcome screens, it will start running as an icon in the tray:
Right-click on the tray icon and select "Add a remote folder".
A dialog appears. In the address field, copy-paste the URL of your Nuxeo server, it is the web address you use to access Nuxeo in your web browser:
Insert the https:// prefix if it did not get copied.
Then enter your Nuxeo username/password.
The next screen shows the Nuxeo folders.
Choose the folder you want to sync.
CmisSync will now sync Nuxeo to your desktop, whenever you have a network connection.
CmisSync does two-way sync, which means you can modify/add files.
Should a conflict occur, a backup is made and you can handle it by choosing which version to keep.